Blocking a protein could help overcome cancer resistance to PARP inhibitors

Researchers at the Francis Crick Institute have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work published in Science , suggests combining treatments could lead to improved therapy for patients with inheritable breast cancers.

Two studies support key role for immune system in shaping SARS-CoV-2 evolution

Two studies published in the open-access journal PLOS Pathogens provide new evidence supporting an important role for the immune system in shaping the evolution of SARS-CoV-2, the virus that causes COVID-19. These findings—and the novel technology behind them—improve understanding of how new SARS-CoV-2 strains arise, which could help guide treatment and vaccination efforts.