Researchers examine how microbes in the gut process the plant-based, sulfur-containing sugar sulfoquinovose

An international team of scientists led by microbiologists Professor Alexander Loy from the University of Vienna and Professor David Schleheck from the University of Konstanz has uncovered new metabolic capabilities of gut bacteria. For the first time, the researchers have analyzed how microbes in the gut process the plant-based, sulfur-containing sugar sulfoquinovose. Sulfoquinovose is a sulfonic acid derivative of glucose and is found in all green vegetables such as spinach and lettuce. Their study discovered that specialized bacteria cooperate in the utilization of the sulfosugar, producing hydrogen sulfide. This gas—known for its rotten egg smell—has disparate effects on human health: at low concentrations, it has an anti-inflammatory effect, while increased amounts of hydrogen sulfide in the intestine, in turn, are associated with diseases such as cancer. The study has been published in the current issue of The ISME Journal.

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