Chimeric tool advanced for wide range of regenerative medicine, biomedical research applications

The ability to grow the cells of one species within an organism of a different species offers scientists a powerful tool for research and medicine. It’s an approach that could advance our understanding of early human development, disease onset and progression and aging; provide innovative platforms for drug evaluation; and address the critical need for …

Couples and young-onset dementia: Study of coping offers hope for new interventions

Researchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diagnosed with young-onset dementia (YOD) and their partners. In a study published in JAMA Network Open, the team conducted in-depth interviews to understand how couples navigate challenges related to YOD. This framework has been used to successfully develop …

Immunotherapy alone extended life for metastatic lung cancer patients with KRAS mutation

Real-word evidence is suggesting, for the first time, the most beneficial treatment courses that could help extend the lives of patients with metastatic non-small cell lung cancer, according to research from the Abramson Cancer Center at the University of Pennsylvania.

A drug already in use in humans corrects obesity in mice

It has long been known that obesity is an inflammatory disease, i.e. a chronic defensive reaction of the body to stress caused by excess nutrients. Based on this knowledge, a group of researchers led by Nabil Djouder, head of the Growth Factors, Nutrients and Cancer Group at the Spanish National Cancer Research Centre (CNIO), decided …

New type of cell contributes to increased understanding of ALS

The causes of the serious muscle disease ALS still remain unknown. Now, researchers at Karolinska Institutet and KTH Royal Institute of Technology, among others, have examined a type of cell in the brain blood vessels that could explain the unpredictable disease origins and dynamics. The results indicate a hitherto unknown connection between the nervous and …