Recovered but RT-PCR-positive individuals unlikely to transmit SARS-CoV-2

(HealthDay)—Individuals who have clinically recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and continue to test positive for viral RNA after completing the recommended isolation period do not appear to be infectious to others, according to a study published online April 22 in JAMA Internal Medicine.

MERS DNA vaccine induces immunity, protects from virus challenge in preclinical model

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given intradermally in abbreviated, low-dose immunization regimen. A similar vaccine candidate was previously shown to be safe and tolerable with a three-dose intramuscular injection …

COVID-19 vaccine development built on $17 billion in NIH funding for vaccine technologies

The unprecedented development of COVID-19 vaccines less than a year after discovery of this virus was enabled by more than $17 billion of research on vaccine technologies funded by the NIH prior to the pandemic, according to new research from Bentley University’s Center for Integration of Science and Industry. The article, titled “NIH funding for …

Among COVID-19 survivors, an increased risk of death, serious illness

As the COVID-19 pandemic has progressed, it has become clear that many survivors—even those who had mild cases—continue to manage a variety of health problems long after the initial infection should have resolved. In what is believed to be the largest comprehensive study of long COVID-19 to date, researchers at Washington University School of Medicine …