From individual receptors toward whole-brain function

In the brain, more than a hundred molecular substances act as transmitters that control communication pathways between nerve cells via thousands of different receptor types. In a review article, an international research team discusses how the activation of certain nerve cell receptors affects neuronal networks in the brain. The authors from Ruhr-Universität Bochum (RUB), Pompeu Fabra University in Barcelona and Oxford University present concepts to quantify receptor-specific modulations of brain states. They have also developed a computer model that can predict the impact of individual receptor types on brain activity.

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