Droperidol most effective sedation medication for agitation with less sides effects

In a randomized, double-blind trial of patients with acute undifferentiated agitation in the emergency department, droperidol was more effective for sedation and was associated with fewer episodes of respiratory depression than lorazepam or either dose of ziprasidone. This is the conclusion of Randomized Double-blind Trial of Intramuscular Droperidol, Ziprasidone, and Lorazepam for Acute Undifferentiated Agitation …

Metabolite fumarate can reveal cell damage: New method to generate fumarate for MRI

A promising new concept published by an interdisciplinary research team in Proceedings of the National Academy of Sciences (PNAS) paves the way for major advances in the field of magnetic resonance imaging (MRI). Their new technique could significantly simplify hyperpolarized MRI, which developed around 20 years ago for observing metabolic processes in the body. The …

Antiviral response: Eosinophils active in immediate defense during influenza A infection

For the first time in published literature, Le Bonheur Children’s Hospital and University of Tennessee Health Science Center (UTHSC) researchers showed that a variety of white blood cells known as eosinophils modify the respiratory barrier during influenza A (IAV) infection, according to a recent paper in the journal Cells. This research could have implications in …

Physical activity reduces cardiovascular risk in rheumatic patients

The risk of developing atherosclerosis—a narrowing of the arteries as cholesterol plaque builds up, leading to obstruction of blood flow—is higher for people with autoimmune rheumatic diseases than for the general population. As a result, they are more likely to have heart attacks and other cardiovascular disorders.

Trial of existing antibiotic for treating Staphylococcus aureus bacteremia begins

A clinical trial to test the antibiotic dalbavancin for safety and efficacy in treating complicated Staphylococcus aureus (S. aureus) bacteremia has begun. The trial will enroll 200 adults hospitalized with complicated S. aureus infection at approximately 20 trial sites around the United States. The trial is being sponsored by the National Institute of Allergy and …

New mouse model provides first platform to study late-onset Alzheimer’s disease

University of California, Irvine biologists have developed a new genetically engineered mouse model, that unlike its predecessors, is based on the most common form of Alzheimer’s disease. The advance holds promise for making new strides against the neurodegenerative disease as cases continue to soar. Their study appears in the journal Nature Communications.