Cholestenone shows antibiotic properties against H. pylori

Helicobacter pylori (H. pylori), a gram-negative pathogen that has infected half of the world’s population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric cancers and malignant lymphoma of the stomach. It can be eradicated in most infected people using a combination of three …

Portopulmonary hypertension in patients with chronic liver disease

Portopulmonary hypertension (PoPH) is a form of pulmonary arterial hypertension (PAH). PoPH occurs in approximately 15% of patients with PAH, and is reportedly found in 2-6% of patients with portal hypertension and 1-2% of patients with liver cirrhosis according to studies from Europe and America. However, the real-world data on PoPH in Japan are largely …