Study finds heart transplantation using donation after cardiac death with NRP

A new study, presented today at the AATS 101st Annual Meeting, found that heart transplantation using donation after cardiac death (DCD) with normothermic regional perfusion (NRP) is feasible in the United States. Broader application of DCD heart transplantation has the potential to increase cardiac allograft availability by 20-30 percent. Over a one-year period, from January 2020 to January 2021, eight heart transplants were performed using cardiopulmonary bypass (CPB) for immediate regional reperfusion and cardiac unloading to accomplish optimal myocardial salvage. All hearts were successfully resuscitated and weaned from CPB with no inotropic support and all were accepted for transplantation. Post-transplant cardiac function was excellent in all recipients.

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