To prevent next pandemic, scientists say we must regulate air like food and water

Humans in the 21st century spend most of their time indoors, but the air we breathe inside buildings is not regulated to the same degree as the food we eat and the water we drink. A group of 39 researchers from 14 countries, including two from the University of Colorado Boulder, say that needs to …

A Z-RNA nanoswitch encoded by ‘junk DNA’ turns-off immune responses against self

In a paper published in the May 13th, 2021 issue of PLOS Genetics, a Z-RNA nanoswitch that regulates interferon immune responses is described. The switch, less than 5 nanometer in length, is based on sequences, called flipons, that change outcomes by altering their three dimensional conformation. The Z-RNA nanoswitch flips from the shorter right-handed A-RNA …

Brain mechanism of curiosity unraveled

Curiosity is the motivational drive for exploring and investigating the unknown and making new discoveries. It is as essential and intrinsic for survival as hunger. Until recently, the brain mechanisms underlying curiosity and novelty seeking behavior were unclear. However, researchers from the Netherlands Institute for Neuroscience have now discovered a new brain circuit underlying curiosity …

A sibling-guided strategy to capture the 3D shape of the human face

A new strategy for capturing the 3D shape of the human face draws on data from sibling pairs and leads to identification of novel links between facial shape traits and specific locations within the human genome. Hanne Hoskens of the Department of Human Genetics at Katholieke Universiteit in Leuven, Belgium, and colleagues present these findings …