New research optimizes body’s own immune system to fight cancer

A groundbreaking study led by engineering and medical researchers at the University of Minnesota Twin Cities shows how engineered immune cells used in new cancer therapies can overcome physical barriers to allow a patient’s own immune system to fight tumors. The research could improve cancer therapies in the future for millions of people worldwide.

The mechanism of action of genes with high mutation frequency in cancer

After the p53 tumor suppressor gene, the genes most frequently found mutated in cancer are those encoding two proteins of the SWI/SNF chromatin remodeling complex. This complex’s function is to ‘accommodate’ the histones that cover the DNA of the chromosomes so that the processes of transcription, DNA repair and replication or chromosome segregation can occur, …