Discovery of circadian rhythm gene in mice could lead to breakthroughs

That internal nagging feeling that drives you to seek sleep at night and wake in the morning to eat, work, and play, is, it turns out, genetic, and it’s not just in people. Nearly every living organism—from animals to plants as well as several microorganisms and fungi—has an internal body clock, or a circadian rhythm.

A genomic single-cell map explains neuronal death in epilepsy

A multidisciplinary team led by researchers from the Spanish Research Council (CSIC) identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy. The study, published in Cell Reports, identifies cell-type specific transcriptional signatures of hyper-excitability and neurodegeneration, providing grounds for improved diagnosis. While the presence of sclerosis is …