Study of severe COVID-19 helps uncover the roots of sepsis

Sepsis is a dreaded, life-threatening condition that can occur when an infection spins out of control. Like a tsunami after an earthquake, sepsis occurs when an infection triggers a dysregulation of the immune system, which leads to widespread organ damage and even death. The condition can result from nearly any kind of infection and afflicts tens of millions each year globally. Scientists don’t fully understand how it develops or how best to stop its progression in patients.

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