The health of your lungs may have a lot to do with the size of your bank account, a new, large study indicates.
Study sheds light on mysterious genotype-phenotype associations
A new study analyzing the association between an individual’s genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases.
Chip inserted under the skin may better identify patients at risk of recurrent stroke
For patients who have experienced certain common types of stroke, a small chip inserted under the skin may help physicians predict their likelihood of experiencing a second stroke, and therefore their likelihood of benefiting from preventive therapy. The findings come from a recent clinical trial published in the Journal of the American Medical Association and …
Researchers discover gene linked to bone cancer in children, ID potential novel therapy
Researchers have discovered a gene, OTUD7A, that impacts the development of Ewing sarcoma, a bone cancer that occurs mainly in children. They have also identified a compound that shows potential to block OTUD7A protein activity. The finding, by scientists at the University of North Carolina and the Lineberger Comprehensive Cancer Center, appeared online June 1, …
Treatabolome project designed to shorten diagnosis-to-treatment time for patients with rare diseases
The Treatabolome project is a research initiative to develop a freely available, interoperable online platform dedicated to disseminating rare disease and gene-specific treatment information to healthcare professionals regardless of their level of specialized expertise. Developed under the Solve-RD European Research Project, it is intended to reduce treatment delays for patients with rare diseases by directly …
Mini bone marrow model predicts response to blood disorder treatment
A new miniature 3D model of human bone marrow has been described today in the open-access eLife journal.
Diet plays critical role in NASH progressing to liver cancer in mouse model
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD patients are at higher risk of developing non-alcoholic steatohepatitis (NASH), which causes severe and chronic liver inflammation, fibrosis and liver damage. A patient with NASH is believed to be at high risk for developing a form of liver cancer …
Scientists identify mechanism linking traumatic brain injury to neurodegenerative disease
Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases, according to a study in fruit flies, and rat and human brain tissue, published today in eLife.
COVID-positive people have more severe strokes, study finds
Among people who have strokes and COVID-19, there is a higher incidence of severe stroke as well as stroke in younger people, according to new data from a multinational study group on COVID-19 and stroke, led by a team of Geisinger researchers.
International study of weight stigma reveals similar, pervasive experiences
Over 50% of adults surveyed across six different countries report experiencing weight stigma, and those who engage in self-stigma and self-blame for their weight are more likely to avoid healthcare, obtain less frequent checkups, and perceive less respect from doctors, according to two new studies from the UConn Rudd Center for Food Policy and Obesity. …