Recently, Prof. Xie Can from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science (HFIPS), in a collaboration with Prof. Yan Xiyun’s lab from the Institute of Biophysics, reported the structural basis of mAb AA98’s inhibition on CD146-mediated endothelial cells (EC) activation and designed higher affinity monoclonal antibody HA98 for cancer treatment.
