Many eye diseases are associated with a restricted blood supply, known as ischaemia, which can lead to blindness. The role of the protein tenascin-C, an extracellular matrix component, in retinal ischaemia was investigated in mice by researchers from Ruhr-Universität Bochum (RUB). They showed that tenascin-C plays a crucial role in damaging the cells responsible for vision following ischaemia. The results were published online by the team in the journal Frontiers in Neuroscience on 20 May 2021.
