What happens in brain cells affected by Alzheimer’s disease?

Affecting over 50 million people, Alzheimer’s disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterized by two factors: beta-amyloid plaques outside the nerve cells and tau proteins. The tau protein stabilizes tube-like structures (microtubules) inside …

Two new types of glial cells found in mouse brain

A team of researchers with members from the University of Basel, Columbia University, New York University and the University of Illinois at Chicago, has discovered two new kinds of glial cells after prodding neural stem cells to wake from dormancy. In their paper published in the journal Science, the group describes their study of dormant …

Thousands of deaths likely if COVID-19 ‘left to run’ in Victoria

New modeling, developed by Burnet Institute, highlights the need to preserve public health measures as a key line of defense against COVID-19 even with high vaccination coverage. It estimates more than 4800 Victorians could die from the virus within 12 months if it were to spread or ‘left to run’ without a public health response.

Vaccination helps protect the unvaccinated from COVID-19

Higher levels of vaccination against COVID-19 were associated with lower rates of infection with SARS-CoV-2 among a group of unvaccinated people of 16 years of age and under, reports a study in Nature Medicine. The findings, based on an analysis of vaccination records and test results from 177 geographically distinct communities in Israel from 6 …

Research identifies potential antiviral compound for COVID-19, flu, other viral infection

UMass Medical School scientists Katherine A. Fitzgerald, Ph.D.; Fiachra Humphries, Ph.D.; and Liraz Galia, Ph.D., working with the British-based pharmaceutical company GlaxoSmithKline, have identified a novel molecule capable of stimulating the innate immune system against SARS-CoV-2 virus. A trigger for the STING (stimulator of interferon genes) pathway, the compound, diamidobenzimidazole (diABZI-4), protected animal models and …