The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, has today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care. The manuscript, “Recommendations for Clinical CYP2D6 Genotyping Allele Selection: A Joint Consensus Recommendation of the …
Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
DOE scientists deploy creativity, speed to disrupt COVID-19
In early 2020, when the novel coronavirus was gaining momentum but had not yet been named a pandemic, computational chemist Marti Head of Oak Ridge National Laboratory—along with scientists and researchers around the globe—abruptly switched her focus to the fight against COVID-19.
New curriculum assessment tool can improve medical education about sexual and gender minority (LGBTQI) populations
Medical education aspires to mitigate bias in future professionals by providing a robust curriculum that includes perspectives and practices for caring for sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender, queer, and intersex (LGBTQI) persons. To provide medical schools with a more systematic, uniform approach to teaching these topics in their curriculum, …
Study shows how certain macrophages dampen anti-tumor immunity
A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system’s cancer-killing CD8+ T cells.
Study shows when people with cerebral palsy are most likely to break bones
Researchers at Michigan Medicine found a subset of middle-aged men with cerebral palsy are up to 5.6 times more likely to suffer fractures than men without the disorder.
Cancer experts answer questions about COVID-19 vaccines
The National Comprehensive Cancer Network (NCCN) today announced the publication of new guidance on COVID-19 vaccines for people with cancer, intended to clear up confusion for patients and caregivers. The new four-page patient guide is based on the latest expert review of evolving evidence.
Cloud computing expands brain sciences
People often think about human behavior in terms of what is happening in the present—reading a newspaper, driving a car, or catching a football. But other dimensions of behavior extend over weeks, months, and years.
Screening uptake may contribute to higher risk of colon cancer for black people
Black people have a higher risk of colorectal cancer than white people, but this risk is likely not due to genetics. Data from a recent study by researchers from the U.S. Department of Veterans Affairs, Regenstrief Institute and Indiana University School of Medicine adds more data to the existing evidence.
Moral disgust leaves us with a ‘bad taste’
When we witness behaviors that violate shared moral norms, our brain inhibits the neurons that control our tongue movements—just as it does when something tastes bad. An international research group led by the Universities of Bologna and Messina came to this result in their study published in the journal of Social, Cognitive and Affective Neuroscience …