Methotrexate users have a reduced immune response to mRNA COVID-19 vaccine
Up to a third of patients taking methotrexate—a common treatment for immune mediated inflammatory conditions such as rheumatoid arthritis and psoriasis/psoriatic arthritis—failed to achieve an adequate immune response to mRNA COVID-19 vaccines in a small study accepted for publication in the journal Annals of Rheumatic Diseases.
