First reported cases of clots in large arteries causing stroke following COVID-19 vaccination

Clots in the arteries (arterial thrombosis) are the most common cause of stroke (ischaemic stroke) and have been reported in detail for the first time in young adults who received the Oxford-AstraZeneca COVID-19 vaccine in a letter from UK stroke specialists published online in Journal of Neurology Neurosurgery & Psychiatry.

Number and relative age of siblings is linked to risk of cardiovascular events

First-born children have a lower risk of cardiovascular events such as heart attacks and strokes than brothers and sisters born later, but people who are part of a large family with many siblings have an increased risk of these events, suggests the results of a large population study in Sweden, published in the online journal …

Methotrexate users have a reduced immune response to mRNA COVID-19 vaccine

Up to a third of patients taking methotrexate—a common treatment for immune mediated inflammatory conditions such as rheumatoid arthritis and psoriasis/psoriatic arthritis—failed to achieve an adequate immune response to mRNA COVID-19 vaccines in a small study accepted for publication in the journal Annals of Rheumatic Diseases.