SARS-CoV-2 infections may trigger antibody responses against multiple virus proteins

All coronaviruses produce four primary structural proteins and multiple nonstructural proteins. However, the majority of antibody-based SARS-CoV-2 research has focused on the spike and nucleocapsid proteins. A study published in PLOS Biology by Anna Heffron, Irene Ong and colleagues at the University of Wisconsin-Madison, U.S., suggests that immune responses may develop against other proteins produced by the SARS-CoV-2 virus.

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