A research group led by Professor Sachie Hiratsuka, of the Institute for Biomedical Research, Shinshu University, has found that a specific sequence of messenger RNA (mRNA), which exists outside cells, binds to receptors on the surface of natural killer (NK) cells and is taken up into the nucleus. The group found that NK cells with …
Better reporting of studies on artificial intelligence
An increasing number of studies on artificial intelligence (AI) are published in the dental and oral sciences but aspects of these studies suffer from a range of limitations. Standards towards reporting, like the recently published CONSORT-AI extension, can help to improve studies in this emerging field. Watch authors Falk Schwendicke and Joachim Krois of the …
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Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity
Acrylamide is a toxic chemical compound that affects the nervous system. It is widely used in industries such as paper production, plastics, and wastewater management, and is also a byproduct of commonl-used food processing methods, which makes human exposure to acrylamide inevitable. Therefore, many studies have focused on understanding the toxic effects of acrylamide and …
Lordstown executives sold millions of dollars in stock before problems became public
Lordstown Motors, the embattled electric truck startup, is facing more scrutiny after several of its top executives sold off millions in dollars of stock prior to its dismal first-quarter earnings report.
‘Suffocating’ cancer: Improved melanoma immunotherapy
Hypoxia, or the inadequate oxygenation of a tissue, is a condition occurring frequently in all solid tumors such as melanoma skin cancer. Melanoma cells are not only able to survive oxygen deprivation, but also to use it to their own advantage by hijacking the anti-tumor immune response and developing resistance mechanisms to conventional anti-cancer therapies. …
Teen programs need to focus on wellbeing, not just academics
The authors of new research say supporting children and young people’s mental health is as important as supporting their academic progress, and that particular attention should be paid to the fact that some young people have struggled more than others.
Adjuvant-free avian influenza vaccines in the works
Avian influenza, an acute viral infectious disease that occurs in poultry such as chickens, ducks, and migratory birds, has been reported to be transmittable to humans. It is difficult to control because it spreads among migratory birds that travel to China, Europe, and elsewhere. Once it is transmitted, it spreads rapidly. Disposing of infected livestock …
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