COVID-19 not the sole cause of excess U.S. deaths in 2020

By the year 2017, the United States was already suffering more excess deaths and more life years lost each year than those associated with the COVID-19 pandemic in 2020, according to research from demographers Samuel Preston of the University of Pennsylvania and Yana Vierboom of the Max Planck Institute for Demographic Research.

Study reveals the 3D structure of human uterine endometrium and adenomyosis tissue

New insights into the three-dimensional (3D) morphology of the human uterine endometrium could advance the understanding of the mechanisms of endometrial regeneration and fertilized egg implantation while clarifying the pathogenesis of menstrual disorders, infertility and endometrium-related diseases such as adenomyosis, endometriosis, endometrial hyperplasia and endometrial cancer.

Physicians debate best management strategy for patient with severe aortic stenosis

In a new Annals ‘Beyond the Guideline’s feature, a cardiologist and a cardiothoracic surgeon debate the risks and benefits of transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) for a patient with severe symptomatic aortic stenosis who is at low risk for surgical death. All ‘Beyond the Guidelines’ features are based on …

Scientists identify severe asthma species, show air pollutant as likely contributor

Asthma afflicts more than 300 million people worldwide. The most severe manifestation, known as non-Th2, or non-atopic childhood asthma, represents the majority of the cases, greater than 85%, particularly in low-income countries, according to Hyunok Choi, an associate professor at the Lehigh University College of Health. Yet, whether non-Th2 is a distinct disease (or endotype) …

Study links structural brain changes to behavioral problems in children who snore

A large study of children has uncovered evidence that behavioral problems in children who snore may be associated with changes in the structure of their brain’s frontal lobe. The findings support early evaluation of children with habitual snoring (snoring three or more nights a week). The research, published in Nature Communications, was supported by the …